Differential contribution of transcriptomic regulatory layers in the definition of neuronal identity. H., Sterne-Weiler, T., Morris, Q., Weatheritt, R. Microexons: at the nexus of nervous system development, behaviour and autism spectrum disorder. This study demonstrates that the neuronal splicing of a microexon in Bak1 reduces apoptosis competence and is necessary for supporting neuronal and animal survival, providing genetic evidence highlighting the essential role of neuronal splicing in brain development and organism survival. Developmental attenuation of neuronal apoptosis by neural-specific splicing of Bak1 microexon. Lin, L., Zhang, M., Stoilov, P., Chen, L. Axonogenesis is coordinated by neuron-specific alternative splicing programming and splicing regulator PTBP2. Beyond proteome diversity: alternative splicing as a regulator of neuronal transcript dynamics. Control of neuronal synapse specification by a highly dedicated alternative splicing program. Alternative splicing programming of axon formation. Alternative splicing regulatory networks: functions, mechanisms, and evolution. Regulation of neuronal differentiation, function, and plasticity by alternative splicing. The neurogenetics of alternative splicing. The evolutionary landscape of alternative splicing in vertebrate species. Variation in alternative splicing across human tissues. Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing. Alternative isoform regulation in human tissue transcriptomes. Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products. An amazing sequence arrangement at the 5′ ends of adenovirus 2 messenger RNA.
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